Mysimba

Mysimba (naltrexone HCI, bupropion HCI)

$140.00

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

Mysimba

Mysimba is a clinically proven weight loss medication designed for adults struggling with obesity or overweight conditions, specifically those with a BMI of 30 or higher, or a BMI of at least 27 with related health issues such as type 2 diabetes or hypertension. This innovative treatment combines two active ingredients, bupropion hydrochloride and naltrexone hydrochloride, which work synergistically to reduce appetite and curb food cravings by acting on the brain’s appetite control centers. This dual action helps patients feel satisfied with less food, making it easier to adhere to a calorie-controlled diet and increase physical activity.

Clinical studies involving around 4,500 patients have demonstrated that Naltrexone significantly enhances weight loss compared to placebo. On average, patients treated with Mysimba lost between 3.7% to 8.1% of their body weight over 28 to 56 weeks, with many achieving at least a 5% reduction in weight—a key benchmark for health benefits. In one study, nearly half of the patients on Mysimba achieved a 5% weight loss, and up to 30% reached a 10% reduction, outperforming placebo groups substantially.

Naltrexone is intended to be used alongside a reduced-calorie diet and increased physical activity, supporting sustainable, long-term weight management. Treatment effectiveness is monitored by healthcare providers, who typically assess progress after 16 weeks; if a patient has not lost at least 5% of their initial body weight by then, discontinuation is considered to explore alternative options.

Ideal for those facing challenges with emotional eating and cravings, Mysimba offers a targeted approach to weight loss by addressing both hunger and the pleasure associated with eating. This makes it a valuable option for individuals seeking an effective adjunct to lifestyle changes to achieve and maintain a healthier weight.

Choose Mysimba to support your weight loss journey with a medication backed by rigorous clinical evidence and tailored to help you regain control over your appetite and cravings for lasting results.

Frequently asked questions

Report side effects to the FDA at (800) FDA-1088
Patients and caregivers may also report side effects to the Safety Call Center at 1-888-236-5445.

How does my subscription work?

After you purchase a care plan, if your doctor prescribes medicines, Allo Health initiates a discreet medication delivery process to the address you provide. The medicines are delivered in a plain brown unlabeled package with only your name and address, ensuring privacy.

Can I change my next delivery date?

Based on the available information, if you want to change your next delivery date on Allo Health Pharmacy, you may be able to do so only before your order has been approved by a doctor. Once the doctor has approved the order, changes to the delivery date or address are generally not possible. 

How long does oxycodone stay in your system?

Urine tests are the most common and can detect oxycodone and its metabolites for 1 to 3 days after use.

Blood tests detect oxycodone for a shorter period, typically 3 to 6 hours, but can sometimes detect it up to 24 hours.

Saliva tests can find oxycodone for about 24 to 36 hours, occasionally up to 4 days.

Hair follicle tests provide the longest detection window, revealing oxycodone use for up to 90 days

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